ORM药物详解(中)-促排期

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LUPRON (leuprolide acetate)醋酸亮丙瑞林（醋酸亮丙瑞林）

Lupron prevents the usual hormone exchange thatcauses follicle production and ovulation. This allows for a very precise and uniform stimulation that results in theincreased production of good quality eggs.

醋酸亮丙瑞林避免平时产生卵泡和排卵的荷尔蒙交换。这能够引起非常精准一致的刺激，导致产生更多高品质的卵。

Possibleside effects: Headache, fatigue, hotflashes.

可能有的副作用：头疼、疲乏、潮热。

Administration: Subcutaneous injection.

施用方法：皮下注射。MENOPUR(human menopausalgonadotropin)

美诺孕（人绝经期促性腺激素）

FOLLISTIMOR GONAL-F (purefollicle stimulating hormone)

重组促卵泡激素或果纳芬（纯促卵泡激素）

A combination of follicle stimulating hormone (FSH)and luteinizing hormone (LH) are used to stimulate growth of the follicle andmaturation of the eggs.

使用卵泡刺激素（FSH）和黄体生成素（LH）的结合，刺激卵泡生长和卵子成熟。

Possibleside effects: Headache, abdominalbloating, fluid retention, increased emotional sensitivity.

可能有的副作用：头疼、腹部气胀、液体潴留、情绪敏感增强。

Administration: Subcutaneous or intramuscularinjection.

施用方法：皮下或肌肉注射。GANIRELIX OR CETROTIDE (GnRH antagonist)

加尼瑞克或思哲凯（促性腺激素释放激素抑制剂）

A GnRH antagonist is taken to inhibit prematureluteinizing hormone (LH) surges and thus prevent ovulation during folliclestimulation.

使用促性腺激素释放激素抑制剂抑制早熟的促黄体激素（LH）飙升，因而在卵泡刺激时防止排卵。

Possibleside effects:  Pain at the injection site.Do not use if you have a latex allergy.

可能有的副作用：注射部位的疼痛。如果您对乳胶过敏，请勿使用。

Administration: Subcutaneous injection.

施用方法：皮下注射。HUMANCHORIONIC GONATROPIN (HCG) –Trigger Shot

人绒毛膜促性腺激素（HCG）——促排针

LUPRON/HCG COMBINATION – Trigger Shot

醋酸亮丙瑞林/HCG结合——促排针

HCG simulates the body's normalLH surge causing the final maturation of the eggs.  It is expected that ovulation will take place37-40 hours after HCG. HCG can be given alone (called Novarel) or it can becombined with Lupron to decrease incidence ofovarian hyperstimulation.

HCG刺激身体正常的黄体生成素高峰的形成，让卵子最终成熟。预期在HCG后37-40个小时会发生排卵。HCG能单独使用（称作Novarel）或和醋酸亮丙瑞林相结合，以减少卵巢过度刺激发生。

Possibleside effects: Low abdominal or pelvic discomfort.

可能有的副作用：下腹部或盆腔不适。

Administration: Subcutaneous injection.

施用方法：皮下注射。

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